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Cathepsin B Is Upregulated and Mediates ECM Degradation in Colon Adenocarcinoma HT29 Cells Overexpressing Snail

During tumor development and ongoing metastasis the acquisition of mesenchymal cell traits by epithelial carcinoma cells is achieved through a programmed phenotypic shift called the epithelial-to-mesenchymal transition, EMT. EMT contributes to increased cancer cell motility and invasiveness mainly t...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Kryczka, Jakub, Papiewska-Pajak, Izabela, Kowalska, M. Anna, Boncela, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468499/
https://ncbi.nlm.nih.gov/pubmed/30818851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030203
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