Secretion of an Argonaute protein by a parasitic nematode and the evolution of its siRNA guides

Extracellular RNA has been proposed to mediate communication between cells and organisms however relatively little is understood regarding how specific sequences are selected for export. Here, we describe a specific Argonaute protein (exWAGO) that is secreted in extracellular vesicles (EVs) released...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Chow, Franklin Wang-Ngai, Koutsovoulos, Georgios, Ovando-Vázquez, Cesaré, Neophytou, Kyriaki, Bermúdez-Barrientos, Jose R, Laetsch, Dominik R, Robertson, Elaine, Kumar, Sujai, Claycomb, Julie M, Blaxter, Mark, Abreu-Goodger, Cei, Buck, Amy H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468290/
https://ncbi.nlm.nih.gov/pubmed/30820541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz142
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