Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex

CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that forms an active complex with cyclin Y (CCNY). Although both proteins have been recently implicated in cancer pathogenesis, it is still unclear how the CDK16/CCNY complex exerts its biologic...

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Gepubliceerd in:Exp Mol Med
Hoofdauteurs: Hernández-Ortega, Sara, Sánchez-Botet, Abril, Quandt, Eva, Masip, Núria, Gasa, Laura, Verde, Gaetano, Jiménez, Javier, Levin, Rebecca S., Rutaganira, Florentine U., Burlingame, Alma L., Wolfgeher, Don, Ribeiro, Mariana P. C., Kron, Stephen J., Shokat, Kevan M., Clotet, Josep
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467995/
https://ncbi.nlm.nih.gov/pubmed/30992425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0242-2
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