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Cation-π interactions between methylated ammonium groups and tryptophan in the CHARMM36 additive force field

Cation-π interactions between tryptophan and choline or trimethylated lysines are vital for many biological processes. The performance of the additive CHARMM36 force field against target quantum mechanical data is shown to reproduces QM equilibrium geometries but required modified Lennard-Jones pote...

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Détails bibliographiques
Publié dans:J Chem Theory Comput
Auteurs principaux: Khan, Hanif M., MacKerell, Alexander D., Reuter, Nathalie
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467778/
https://ncbi.nlm.nih.gov/pubmed/30562013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00839
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