Spleen tyrosine kinase-mediated autophagy is required for epithelial-mesenchymal plasticity and metastasis in breast cancer

The ability of breast cancer cells to transiently transition between epithelial and mesenchymal states contributes to their metastatic potential. Therefore, driving tumor cells into a stable mesenchymal state, as opposed to complete tumor cell eradication, presents an opportunity to pharmacologicall...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Shinde, Aparna, Hardy, Shana D., Kim, Dongwook, Akhand, Saeed Salehin, Jolly, Mohit Kumar, Wang, Wen-Hung, Anderson, Joshua C., Khodadadi, Ryan B., Brown, Wells S., George, Jason T., Liu, Sheng, Wan, Jun, Levine, Herbert, Willey, Christopher D., Krusemark, Casey J., Geahlen, Robert L., Wendt, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467765/
https://ncbi.nlm.nih.gov/pubmed/30733195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2636
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