Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors

PURPOSE: Epigenetic regulating proteins like histone methyltransferases produce variations in several functions, some of them associated with the generation of oncogenic processes. Mutations of genes involved in these functions have been recently associated with cancer, and strategies to modulate th...

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Vydáno v:PLoS One
Hlavní autoři: Morcillo-Garcia, Sara, Noblejas-Lopez, Maria del Mar, Nieto-Jimenez, Cristina, Perez-Peña, Javier, Nuncia-Cantarero, Miriam, Győrffy, Balázs, Amir, Eitan, Pandiella, Atanasio, Galan-Moya, Eva M., Ocana, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467442/
https://ncbi.nlm.nih.gov/pubmed/30990809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209134
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