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Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors

PURPOSE: Epigenetic regulating proteins like histone methyltransferases produce variations in several functions, some of them associated with the generation of oncogenic processes. Mutations of genes involved in these functions have been recently associated with cancer, and strategies to modulate th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morcillo-Garcia, Sara, Noblejas-Lopez, Maria del Mar, Nieto-Jimenez, Cristina, Perez-Peña, Javier, Nuncia-Cantarero, Miriam, Győrffy, Balázs, Amir, Eitan, Pandiella, Atanasio, Galan-Moya, Eva M., Ocana, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467442/
https://ncbi.nlm.nih.gov/pubmed/30990809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209134
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