Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

Sleep disordered breathing (SDB)-related overnight hypoxemia is associated with cardiometabolic disease and other comorbidities. Understanding the genetic bases for variations in nocturnal hypoxemia may help understand mechanisms influencing oxygenation and SDB-related mortality. We conducted genome...

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Publicado en:PLoS Genet
Main Authors: Cade, Brian E., Chen, Han, Stilp, Adrienne M., Louie, Tin, Ancoli-Israel, Sonia, Arens, Raanan, Barfield, Richard, Below, Jennifer E., Cai, Jianwen, Conomos, Matthew P., Evans, Daniel S., Frazier-Wood, Alexis C., Gharib, Sina A., Gleason, Kevin J., Gottlieb, Daniel J., Hillman, David R., Johnson, W. Craig, Lederer, David J., Lee, Jiwon, Loredo, Jose S., Mei, Hao, Mukherjee, Sutapa, Patel, Sanjay R., Post, Wendy S., Purcell, Shaun M., Ramos, Alberto R., Reid, Kathryn J., Rice, Ken, Shah, Neomi A., Sofer, Tamar, Taylor, Kent D., Thornton, Timothy A., Wang, Heming, Yaffe, Kristine, Zee, Phyllis C., Hanis, Craig L., Palmer, Lyle J., Rotter, Jerome I., Stone, Katie L., Tranah, Gregory J., Wilson, James G., Sunyaev, Shamil R., Laurie, Cathy C., Zhu, Xiaofeng, Saxena, Richa, Lin, Xihong, Redline, Susan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467367/
https://ncbi.nlm.nih.gov/pubmed/30990817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007739
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