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SLC and ABC Transporters: Expression, Localization, and Species Differences at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers

The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB) separate the brain and cerebrospinal fluid (CSF) from the systemic circulation and represent a barrier to the uptake of both endogenous compounds and xenobiotics into the brain. For compounds whose passive diffusion is l...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Morris, Marilyn E., Rodriguez-Cruz, Vivian, Felmlee, Melanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467070/
https://ncbi.nlm.nih.gov/pubmed/28664465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-017-0110-8
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