Real-Time Interrogation of Aspirin Reactivity, Biochemistry, and Biodistribution by Hyperpolarized Magnetic Resonance Spectroscopy

Hyperpolarized magnetic resonance spectroscopy enables quantitative, non-radioactive, real-time measurement of imaging probe biodistribution and metabolism in vivo. Here, we investigate and report on the development and characterization of hyperpolarized acetylsalicylic acid (aspirin) and its use as...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Zacharias, Niki M., Ornelas, Argentina, Lee, Jaehyuk, Hu, Jingzhe, Davis, Jennifer S., Uddin, Nasir, Pudakalakatti, Shivanand, Menter, David G., Karam, Jose A., Wood, Christopher G., Hawk, Ernest T., Kopetz, Scott, Vilar, Eduardo, Bhattacharya, Pratip K., Millward, Steven W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467058/
https://ncbi.nlm.nih.gov/pubmed/30680862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201812759
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