Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector

BACKGROUND: A robust scalable method for producing enucleated red blood cells (RBCs) is not only a process to produce packed RBC units for transfusion but a potential platform to produce modified RBCs with applications in advanced cellular therapy. Current strategies for producing RBCs have shortcom...

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Vydáno v:BMC Biotechnol
Hlavní autoři: Mayers, Steven, Moço, Pablo Diego, Maqbool, Talha, Silva, Pamuditha N., Kilkenny, Dawn M., Audet, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466758/
https://ncbi.nlm.nih.gov/pubmed/30987611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0515-9
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