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Depletion of PCAT-1 in head and neck cancer cells inhibits tumor growth and induces apoptosis by modulating c-Myc-AKT1-p38 MAPK signalling pathways

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) represents one of the most common malignancies worldwide with a high mortality rate mainly due to lack of early detection markers, frequent association with metastasis and aggressive phenotype. Recently, long non-coding RNAs (lncRNAs) have be...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Sur, Subhayan, Nakanishi, Hiroshi, Steele, Robert, Ray, Ratna B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466688/
https://ncbi.nlm.nih.gov/pubmed/30987615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5562-z
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