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Mouse germ line mutations due to retrotransposon insertions

Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape in mouse contrasts with the situation in human, where their relative contribution as germ li...

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Udgivet i:Mob DNA
Main Authors: Gagnier, Liane, Belancio, Victoria P., Mager, Dixie L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466679/
https://ncbi.nlm.nih.gov/pubmed/31011371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-019-0157-4
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