Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials

BACKGROUND: Irritable bowel syndrome with diarrhea (IBS-D) is a prevalent gastrointestinal (GI) disorder with a varied presentation, often overlapping with other GI and non-GI disorders. Eluxadoline is a locally active mixed µ- and κ-opioid receptor agonist and δ-opioid receptor antagonist approved...

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Dettagli Bibliografici
Pubblicato in:Therap Adv Gastroenterol
Autori principali: Lacy, Brian E., Harris, Lucinda A., Chang, Lin, Lucak, Susan, Gutman, Catherine, Dove, Leonard S., Covington, Paul S., Lembo, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466471/
https://ncbi.nlm.nih.gov/pubmed/31019552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284819841290
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