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Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol
The ‘Appelmans protocol’ is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of mostly refractory bacterial isolates until the evolved cocktail can lyse the phage-resistant strains. To study this proces...
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| Udgivet i: | Viruses |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6466182/ https://ncbi.nlm.nih.gov/pubmed/30862096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11030241 |
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