The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-Cell Leukaemia

We have previously shown that antibody-dependent cellular cytotoxicity (ADCC) cooperates with immunotoxin (IT)-mediated killing of human leukaemia cells in an severe combined immunodeficient (SCID) mouse model of human T-cell acute lymphoblastic leukaemia (SCID-HSB-2 mice), but not in an equivalent...

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Bibliografiset tiedot
Julkaisussa:Biomedicines
Päätekijät: Flavell, David J., Holmes, Suzanne E., Warnes, Sarah L, Flavell, Sopsamorn U.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466153/
https://ncbi.nlm.nih.gov/pubmed/30781517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines7010013
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