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Prion Variants of Yeast are Numerous, Mutable, and Segregate on Growth, Affecting Prion Pathogenesis, Transmission Barriers, and Sensitivity to Anti-Prion Systems

The known amyloid-based prions of Saccharomyces cerevisiae each have multiple heritable forms, called “prion variants” or “prion strains”. These variants, all based on the same prion protein sequence, differ in their biological properties and their detailed amyloid structures, although each of the f...

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Bibliografski detalji
Izdano u:Viruses
Glavni autori: Wickner, Reed B., Son, Moonil, Edskes, Herman K.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466074/
https://ncbi.nlm.nih.gov/pubmed/30857327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11030238
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