A Single V672F Substitution in the Spike Protein of Field-Isolated PEDV Promotes Cell–Cell Fusion and Replication in VeroE6 Cells

While porcine epidemic diarrhea virus (PEDV) infects and replicates in enterocytes lining villi of neonatal piglets with high efficiency, naturally isolated variants typically grow poorly in established cell lines, unless adapted by multiple passages. Cells infected with most cell-adapted PEDVs usua...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Wanitchang, Asawin, Saenboonrueng, Janya, Kaewborisuth, Challika, Srisutthisamphan, Kanjana, Jongkaewwattana, Anan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466060/
https://ncbi.nlm.nih.gov/pubmed/30897856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11030282
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