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Depressive Symptoms After PCB Exposure: Hypotheses for Underlying Pathomechanisms via the Thyroid and Dopamine System

Polychlorinated biphenyls’ (PCB) exposure has been reported to be associated with depressive symptoms, which is correlated to lower dopamine- (DA) and thyroxine-concentrations (T4). T4 is necessary for DA-synthesis and it binds to transthyretin (TTR) being transported into the brain. PCBs can displa...

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Bibliographic Details
Published in:Int J Environ Res Public Health
Main Authors: Gaum, Petra Maria, Gube, Monika, Esser, André, Schettgen, Thomas, Quinete, Natalia, Bertram, Jens, Putschögl, Franziska Maria, Kraus, Thomas, Lang, Jessica
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466013/
https://ncbi.nlm.nih.gov/pubmed/30884813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph16060950
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