Bovine Herpesvirus Type 4 (BoHV-4) Vector Delivering Nucleocapsid Protein of Crimean-Congo Hemorrhagic Fever Virus Induces Comparable Protective Immunity against Lethal Challenge in IFNα/β/γR−/− Mice Models

Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of a tick-borne infection with a significant mortality rate of up to 40% in endemic areas, with evidence of geographical expansion. Due to a lack of effective therapeutics and control measures, the development of a protective CCHFV...

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Publicat a:Viruses
Autors principals: Aligholipour Farzani, Touraj, Földes, Katalin, Hanifehnezhad, Alireza, Yener Ilce, Burcu, Bilge Dagalp, Seval, Amirzadeh Khiabani, Neda, Ergünay, Koray, Alkan, Feray, Karaoglu, Taner, Bodur, Hurrem, Ozkul, Aykut
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466008/
https://ncbi.nlm.nih.gov/pubmed/30857305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11030237
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