KLRG1(+) Effector CD8(+) T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

Protective immunity against pathogens depends on the efficient generation of functionally diverse effector and memory T lymphocytes. However, whether plasticity during effector-to-memory CD8(+) T cell differentiation affects memory lineage specification and functional versatility remains unclear. Us...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Herndler-Brandstetter, Dietmar, Ishigame, Harumichi, Shinnakasu, Ryo, Plajer, Valerie, Stecher, Carmen, Zhao, Jun, Lietzenmayer, Melanie, Kroehling, Lina, Takumi, Akiko, Kometani, Kohei, Inoue, Takeshi, Kluger, Yuval, Kaech, Susan M., Kurosaki, Tomohiro, Okada, Takaharu, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465538/
https://ncbi.nlm.nih.gov/pubmed/29625895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.03.015
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