SLC6A4 Repeat and Single-Nucleotide Polymorphisms Are Associated With Depression and Rest Tremor in Parkinson's Disease: An Exploratory Study

Introduction: Level of serotonin is mainly regulated by the serotonin reuptake transporter encoded by SLC6A4. The promoter region of SLC6A4 bears a repeat polymorphism 5-HTTLPR and a single nucleotide polymorphism rs25531. We have previously studied the association between these two variants and spo...

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Pubblicato in:Front Neurol
Autori principali: Wang, Jian-Yong, Fan, Qian-Ya, He, Jia-Hui, Zhu, Shi-Guo, Huang, Chen-Ping, Zhang, Xiong, Zhu, Jian-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Neurology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465511/
https://ncbi.nlm.nih.gov/pubmed/31024427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00333
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