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Artonin E sensitizes TRAIL-induced apoptosis by DR5 upregulation and cFLIP downregulation in TRAIL-refractory colorectal cancer LoVo cells

BACKGROUND: The TRAIL treatment is an ideal strategy for colorectal cancer (CRC) therapy because of minimal collateral damage to normal cells. Unfortunately, some CRC is TRAIL-refractory cancer, such as LoVo cells. In an effort to overcome TRAIL-refractory cancer, we investigated the effect of arton...

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Bibliografiske detaljer
Udgivet i:J Gastrointest Oncol
Main Authors: Sophonnithiprasert, Thanet, Mahabusarakam, Wilawan, Watanapokasin, Ramida
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465495/
https://ncbi.nlm.nih.gov/pubmed/31032087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2018.12.02
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