A novel approach to differentiate rat embryonic stem cells in vitro reveals a role for RNF12 in activation of X chromosome inactivation

X chromosome inactivation (XCI) is a mammalian specific, developmentally regulated process relying on several mechanisms including antisense transcription, non-coding RNA-mediated silencing, and recruitment of chromatin remodeling complexes. In vitro modeling of XCI, through differentiation of embry...

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Publicado en:Sci Rep
Autores principales: Magaraki, Aristea, Loda, Agnese, Gontan, Cristina, Merzouk, Sarra, Sleddens-Linkels, Esther, Meek, Stephen, Baarends, Willy M., Burdon, Tom, Gribnau, Joost
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465393/
https://ncbi.nlm.nih.gov/pubmed/30988473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42246-2
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