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Characterising side chains in large proteins by protonless (13)C-detected NMR spectroscopy

Side chains cover protein surfaces and are fundamental to processes as diverse as substrate recognition, protein folding and enzyme catalysis. However, characterisation of side-chain motions has so far been restricted to small proteins and methyl-bearing side chains. Here we present a class of metho...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pritchard, Ruth B., Hansen, D. Flemming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465260/
https://ncbi.nlm.nih.gov/pubmed/30988305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09743-4
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