Lipid microenvironment affects the ability of proteoliposomes harboring TNAP to induce mineralization without nucleators

Tissue-nonspecific alkaline phosphatase (TNAP), a glycosylphosphatidylinositol-anchored ectoenzyme present on the membrane of matrix vesicles (MVs), hydrolyzes the mineralization inhibitor inorganic pyrophosphate as well as ATP to generate the inorganic phosphate needed for apatite formation. Herein...

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Библиографические подробности
Опубликовано в: :J Bone Miner Metab
Главные авторы: Simão, Ana Maria Sper, Bolean, Maytê, Favarin, Bruno Zoccaratto, Veschi, Ekeveliny Amabile, Tovani, Camila Bussola, Ramos, Ana Paula, Bottini, Massimo, Buchet, Rene, Millán, José Luis, Ciancaglini, Pietro
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465158/
https://ncbi.nlm.nih.gov/pubmed/30324534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00774-018-0962-8
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