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Lipid microenvironment affects the ability of proteoliposomes harboring TNAP to induce mineralization without nucleators
Tissue-nonspecific alkaline phosphatase (TNAP), a glycosylphosphatidylinositol-anchored ectoenzyme present on the membrane of matrix vesicles (MVs), hydrolyzes the mineralization inhibitor inorganic pyrophosphate as well as ATP to generate the inorganic phosphate needed for apatite formation. Herein...
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| Publicado no: | J Bone Miner Metab |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465158/ https://ncbi.nlm.nih.gov/pubmed/30324534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00774-018-0962-8 |
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