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mRNA 5’ ends targeted by cytoplasmic recapping cluster at CAGE tags and select transcripts are alternatively spliced

Until cytoplasmic recapping was discovered, decapping was thought to irreversibly destine an mRNA to degradation. Contradicting this idea, we readily observe mRNAs targeted by cytoplasmic capping in uncapped, yet stable forms. 5’ RACE shows that nearly all uncapped ends correspond to CAGE (capped an...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Berger, Mikaela R., Alvarado, Rolando, Kiss, Daniel L.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465107/
https://ncbi.nlm.nih.gov/pubmed/30810230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13349
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