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Karyopherin Msn5 is involved in a novel mechanism controlling the cellular level of cell cycle regulators Cln2 and Swi5

The yeast β-karyopherin Msn5 controls the SBF cell-cycle transcription factor, responsible for the periodic expression of CLN2 cyclin gene at G1/S, and the nuclear export of Cln2 protein. Here we show that Msn5 regulates Cln2 by an additional mechanism. Inactivation of Msn5 causes a severe reduction...

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Publicat a:Cell Cycle
Autors principals: Quilis, Inma, Taberner, Francisco J., Martínez-Garay, Carlos A., Alepuz, Paula, Igual, J. Carlos
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464581/
https://ncbi.nlm.nih.gov/pubmed/30739521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1578148
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