An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle

Genome editing techniques have facilitated significant advances in our understanding of fundamental biological processes, and the Cre-Lox system has been instrumental in these achievements. Driving Cre expression specifically in injured neurons has not been previously possible: we sought to address...

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Dettagli Bibliografici
Pubblicato in:eNeuro
Autori principali: Holland, Seth D., Ramer, Leanne M., McMahon, Stephen B., Denk, Franziska, Ramer, Matt S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2019
Soggetti:
Methods/New Tools
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464513/
https://ncbi.nlm.nih.gov/pubmed/30993183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0025-19.2019
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