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Anti‐IL‐12/23p40 antibodies for induction of remission in Crohn's disease

BACKGROUND: Ustekinumab (CNTO 1275) and briakinumab (ABT‐874) are monoclonal antibodies that target the standard p40 subunit of the cytokines interleukin‐12 and interleukin‐23 (IL‐12/23p40), which are involved in the pathogenesis of Crohn's disease. OBJECTIVES: The objectives of this review wer...

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Detalhes bibliográficos
Publicado no:Cochrane Database Syst Rev
Main Authors: MacDonald, John K, Nguyen, Tran M, Khanna, Reena, Timmer, Antje
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464484/
https://ncbi.nlm.nih.gov/pubmed/27885650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD007572.pub3
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