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Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association

Human CTC1-STN1-TEN1 (CST) is an RPA-like single-stranded DNA-binding protein that interacts with DNA polymerase α-primase (pol α) and functions in telomere replication. Previous studies suggest that CST also promotes replication restart after fork stalling. However, the precise role of CST in genom...

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Publicado en:Life Sci Alliance
Autores principales: Wang, Yilin, Brady, Kathryn S, Caiello, Benjamin P, Ackerson, Stephanie M, Stewart, Jason A
Formato: Artigo
Lenguaje:Inglês
Publicado: Life Science Alliance LLC 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464128/
https://ncbi.nlm.nih.gov/pubmed/30979824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800270
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