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Generation of a Potent Recombinant Homophilic Chimeric Anti-CD20 Antibody

Previously we increased the potency of therapeutic antibodies in targeting, induction of apoptosis, and growth inhibition in vitro and in vivo by chemically conjugating a homophilic peptide to the antibody. Here, we describe the construction of a chimeric fusion gene derived from the murine anti-CD2...

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Publicado en:Hybridoma (Larchmt)
Autores principales: Kohler, Heinz, Rector, Kyle, Amick, Jean
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463998/
https://ncbi.nlm.nih.gov/pubmed/23244317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hyb.2012.0073
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