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G protein–coupled receptors activate p38 MAPK via a non-canonical TAB1–TAB2– and TAB1–TAB3–dependent pathway in endothelial cells

Endothelial dysfunction is induced by inflammatory mediators including multiple G protein–coupled receptor (GPCR) agonists. However, the GPCR signaling pathways that promote endothelial dysfunction are incompletely understood. We previously showed that thrombin promotes endothelial barrier disruptio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Grimsey, Neil J., Lin, Ying, Narala, Rachan, Rada, Cara C., Mejia-Pena, Hilda, Trejo, JoAnn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463731/
https://ncbi.nlm.nih.gov/pubmed/30760523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007495
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