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Structural and biochemical insights into the catalytic mechanisms of two insect chitin deacetylases of the carbohydrate esterase 4 family

Insect chitin deacetylases (CDAs) catalyze the removal of acetyl groups from chitin and modify this polymer during its synthesis and reorganization. CDAs are essential for insect survival and therefore represent promising targets for insecticide development. However, the structural and biochemical c...

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Publicado en:J Biol Chem
Autores principales: Liu, Lin, Zhou, Yong, Qu, Mingbo, Qiu, Yu, Guo, Xingming, Zhang, Yuebin, Liu, Tian, Yang, Jun, Yang, Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463723/
https://ncbi.nlm.nih.gov/pubmed/30755482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007597
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