Structural and biochemical insights into the catalytic mechanisms of two insect chitin deacetylases of the carbohydrate esterase 4 family

Insect chitin deacetylases (CDAs) catalyze the removal of acetyl groups from chitin and modify this polymer during its synthesis and reorganization. CDAs are essential for insect survival and therefore represent promising targets for insecticide development. However, the structural and biochemical c...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Liu, Lin, Zhou, Yong, Qu, Mingbo, Qiu, Yu, Guo, Xingming, Zhang, Yuebin, Liu, Tian, Yang, Jun, Yang, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463723/
https://ncbi.nlm.nih.gov/pubmed/30755482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007597
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