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A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils
The tetrameric protein transthyretin is a transporter of retinol and thyroxine in blood, cerebrospinal fluid, and the eye, and is secreted by the liver, choroid plexus, and retinal epithelium, respectively. Systemic amyloid deposition of aggregated transthyretin causes hereditary and sporadic amyloi...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463714/ https://ncbi.nlm.nih.gov/pubmed/30733338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005257 |
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