The regulatory protein GADD34 inhibits TRAIL-induced apoptosis via TRAF6/ERK-dependent stabilization of myeloid cell leukemia 1 in liver cancer cells

GADD34 (growth arrest and DNA damage-inducible gene 34) plays a critical role in responses to DNA damage and endoplasmic reticulum stress. GADD34 has opposing effects on different stimuli-induced cell apoptosis events, but the reason for this is unclear. Here, using immunoblotting analyses and vario...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Song, Peiying, Yang, Songpeng, Hua, Hui, Zhang, Hongying, Kong, Qingbin, Wang, Jiao, Luo, Ting, Jiang, Yangfu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463698/
https://ncbi.nlm.nih.gov/pubmed/30782845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006029
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