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Egr1 mediates the effect of insulin on leptin transcription in adipocytes
In mammals, leptin production in adipocytes is up-regulated by feeding and insulin. Although this regulatory connection is central to all physiological effects of leptin, its molecular mechanism remains unknown. Here, we show that the transcription factor early growth response 1, Egr1, is rapidly bu...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6463691/ https://ncbi.nlm.nih.gov/pubmed/30846562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.007855 |
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