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Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment

BACKGROUND: Pancreatic cancer is one of the most lethal type of cancers, with an overall five-year survival rate of less than 5%. It is usually diagnosed at an advanced stage with limited therapeutic options. To date, no effective treatment options have demonstrated long-term benefits in advanced pa...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Looi, Chin-King, Chung, Felicia Fei-Lei, Leong, Chee-Onn, Wong, Shew-Fung, Rosli, Rozita, Mai, Chun-Wai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463646/
https://ncbi.nlm.nih.gov/pubmed/30987642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1153-8
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