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Osteochondritis Dissecans (OCD)-Derived Chondrocytes Display Increased Senescence, Oxidative Stress, Chaperone-Mediated Autophagy and, in Co-Culture with Adipose-Derived Stem Cells (ASCs), Enhanced Expression of MMP-13

Osteochondritis dissecans (OCD) in equids, especially in sport horses, has become a growing issue as it contributes to the occurrence of lameness. Thus the aim of this study was to investigate the cytophysiological properties of OCD chondrocytes including expression of chondrogenic genes, apoptosis,...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Kornicka, Katarzyna, Al Naem, Mohamad, Röcken, Michael, Zmiertka, Marta, Marycz, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462951/
https://ncbi.nlm.nih.gov/pubmed/30857162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8030328
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