Calcium-Activated Calpain Specifically Cleaves Glutamate Receptor IIA But Not IIB at the Drosophila Neuromuscular Junction

Calpains are calcium-dependent, cytosolic proteinases active at neutral pH. They do not degrade but cleave substrates at limited sites. Calpains are implicated in various pathologies, such as ischemia, injuries, muscular dystrophy, and neurodegeneration. Despite so, the physiological function of cal...

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Vydáno v:J Neurosci
Hlavní autoři: Metwally, Elsayed, Zhao, Guoli, Li, Wenhua, Wang, Qifu, Zhang, Yong Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462441/
https://ncbi.nlm.nih.gov/pubmed/30705102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2213-17.2019
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