Pharmacokinetics and Biodistribution of Rhopalurus junceus Scorpion Venom in Tumor-Bearing Mice after Intravenous and Oral Administration

INTRODUCTION: Rhopalurus junceus scorpion venom has shown potential for anticancer treatment. However, there are no scientific evidence about venom pharmacokinetic (PK) and biodistribution (BD) in tumor-bearing mice. METHODS: (131)I-labeled venom was administrated by intravenous (IV) and oral (PO) r...

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Udgivet i:Iran Biomed J
Main Authors: Díaz-García, Alexis, González, Gilmara Pimentel, Bernabeu, Tais Basaco, Aurrecochea, Juan C. Rodríguez, Sánchez, Hermis Rodríguez, Monzón, Iraida Sánchez, Gómez, Maikel Hernández, Torres, Caridad Rodríguez, Capote, Maria Regla Rodríguez, Orellanes, Irania Guevara
Format: Artigo
Sprog:Inglês
Udgivet: Pasteur Institute 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462292/
https://ncbi.nlm.nih.gov/pubmed/30954030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/.23.4.287
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