Selective delipidation of Mycobacterium bovis BCG enables direct pulmonary vaccination and enhances protection against Mycobacterium tuberculosis

Mycobacterium tuberculosis (M.tb), the causative agent of tuberculosis (TB), is the leading killer due to an infectious organism. Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine approved against TB, however, its efficacy against pulmonary TB is poor. While BCG is currently ino...

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Publicat a:Mucosal Immunol
Autors principals: Moliva, Juan I., Hossfeld, Austin P., Sidiki, Sabeen, Canan, Cynthia H., Dwivedi, Varun, Beamer, Gillian, Turner, Joanne, Torrelles, Jordi B.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462255/
https://ncbi.nlm.nih.gov/pubmed/30778118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0148-2
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