Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages

Long noncoding RNAs (lncRNAs) impart significant regulatory functions in a diverse array of biological pathways and manipulation of these RNAs provides an important avenue to modulate such pathways, particularly in disease. Our knowledge about lncRNAs’ role in determination of cellular fate during H...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Boliar, Saikat, Gludish, David W., Jambo, Kondwani C., Kamng’ona, Raphael, Mvaya, Leonard, Mwandumba, Henry C., Russell, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462110/
https://ncbi.nlm.nih.gov/pubmed/30918127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818662116
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