Targeting pericyte–endothelial cell crosstalk by circular RNA-cPWWP2A inhibition aggravates diabetes-induced microvascular dysfunction

The crosstalk between vascular pericytes and endothelial cells (ECs) is critical for microvascular stabilization and remodeling; however, the crosstalk is often disrupted by diabetes, leading to severe and even lethal vascular damage. Circular RNAs are a class of endogenous RNAs that regulate severa...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Liu, Chang, Ge, Hui-Min, Liu, Bai-Hui, Dong, Rui, Shan, Kun, Chen, Xue, Yao, Mu-Di, Li, Xiu-Miao, Yao, Jin, Zhou, Rong-Mei, Zhang, Shu-Jie, Jiang, Qin, Zhao, Chen, Yan, Biao
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462073/
https://ncbi.nlm.nih.gov/pubmed/30914462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814874116
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