Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression

Obsessive-compulsive disorder (OCD) is a severe, chronic neuropsychiatric disorder with a strong genetic component. The SLC1A1 gene encoding the neuronal glutamate transporter EAAT3 has been proposed as a candidate gene for this disorder. Gene variants affecting SLC1A1 expression in human brain tiss...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Delgado-Acevedo, Claudia, Estay, Sebastián F., Radke, Anna K., Sengupta, Ayesha, Escobar, Angélica P., Henríquez-Belmar, Francisca, Reyes, Cristopher A., Haro-Acuña, Valentina, Utreras, Elías, Sotomayor-Zárate, Ramón, Cho, Andrew, Wendland, Jens R., Kulkarni, Ashok B., Holmes, Andrew, Murphy, Dennis L., Chávez, Andrés E., Moya, Pablo R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462043/
https://ncbi.nlm.nih.gov/pubmed/30622300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0302-7
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