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KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

Despite more effective chemotherapy combined with limb-salvage surgery for the osteosarcoma treatment, survival rates for osteosarcoma patients have stagnated over the past three decades due to the poor prognosis. Osteosarcoma cancer stem cells (OSCs) are responsible for the growth and metastasis of...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Qi, Xiao-tian, Li, Yang-ling, Zhang, Yan-qi, Xu, Tong, Lu, Bin, Fang, Liang, Gao, Jian-qing, Yu, Lu-shan, Zhu, Di-feng, Yang, Bo, He, Qiao-jun, Ying, Mei-dan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461873/
https://ncbi.nlm.nih.gov/pubmed/29930276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0050-6
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