HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen

Acetaminophen (APAP) overdose (APAPo) is predominant in the NIH Pediatric Acute Liver Failure (PALF) Study. We assayed multiple inflammatory mediators in serial serum samples from 13 PALF survivors with APAPo + N-acetylcysteine (NAC, the frontline therapy for APAPo), 8 non-APAPo + NAC, 40 non-APAPo...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zamora, Ruben, Barclay, Derek, Yin, Jinling, Alonso, Estella M., Leonis, Mike A., Mi, Qi, Billiar, Timothy R., Simmons, Richard L., Squires, Robert H., Vodovotz, Yoram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461628/
https://ncbi.nlm.nih.gov/pubmed/30979951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42564-5
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