HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen

Acetaminophen (APAP) overdose (APAPo) is predominant in the NIH Pediatric Acute Liver Failure (PALF) Study. We assayed multiple inflammatory mediators in serial serum samples from 13 PALF survivors with APAPo + N-acetylcysteine (NAC, the frontline therapy for APAPo), 8 non-APAPo + NAC, 40 non-APAPo...

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Publicado en:Sci Rep
Main Authors: Zamora, Ruben, Barclay, Derek, Yin, Jinling, Alonso, Estella M., Leonis, Mike A., Mi, Qi, Billiar, Timothy R., Simmons, Richard L., Squires, Robert H., Vodovotz, Yoram
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461628/
https://ncbi.nlm.nih.gov/pubmed/30979951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42564-5
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