Helicobacter pylori Vacuolating Cytotoxin A Causes Anorexia and Anxiety via Hypothalamic Urocortin 1 in Mice

Helicobacter pylori (Hp) infection is related to the pathogenesis of chronic gastric disorders and extragastric diseases. Here, we examined the anorexigenic and anxiogenic effects of Hp vacuolating cytotoxin A (VacA) through activation of hypothalamic urocortin1 (Ucn1). VacA was detected in the hypo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Suzuki, Hajime, Ataka, Koji, Asakawa, Akihiro, Cheng, Kai-Chun, Ushikai, Miharu, Iwai, Haruki, Yagi, Takakazu, Arai, Takeshi, Yahiro, Kinnosuke, Yamamoto, Katsuhiro, Yokoyama, Yoshito, Kojima, Masayasu, Yada, Toshihiko, Hirayama, Toshiya, Nakamura, Norifumi, Inui, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461611/
https://ncbi.nlm.nih.gov/pubmed/30979915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42163-4
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