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Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors

Cell-free transcription–translation systems have great potential for biosensing, yet the range of detectable chemicals is limited. Here we provide a workflow to expand the range of molecules detectable by cell-free biosensors through combining synthetic metabolic cascades with transcription factor-b...

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Publicat a:Nat Commun
Autors principals: Voyvodic, Peter L., Pandi, Amir, Koch, Mathilde, Conejero, Ismael, Valjent, Emmanuel, Courtet, Philippe, Renard, Eric, Faulon, Jean-Loup, Bonnet, Jerome
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461607/
https://ncbi.nlm.nih.gov/pubmed/30979906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09722-9
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