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Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry

Wolfram syndrome is a rare disease caused by mutations in the WFS1 gene leading to symptoms in early to mid-childhood. Brain structural abnormalities are present even in young children, but it is not known when these abnormalities arise. Such information is critical in determining optimal outcome me...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lugar, Heather M., Koller, Jonathan M., Rutlin, Jerrel, Eisenstein, Sarah A., Neyman, Olga, Narayanan, Anagha, Chen, Ling, Shimony, Joshua S., Hershey, Tamara
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461605/
https://ncbi.nlm.nih.gov/pubmed/30979932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42447-9
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