siRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice

BACKGROUND: The costimulatory CD40-CD40L pathway plays a role in kidney inflammation. We have previously reported that renal CD40 upregulation precedes cellular interstitial infiltrate and fibrosis in the unilateral ureteral obstruction (UUO) model. Here we sought to evaluate whether the administrat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Narváez, Alonso, Guiteras, Roser, Sola, Anna, Manonelles, Anna, Morote, Juan, Torras, Juan, Grinyó, Josep M., Cruzado, Josep M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461348/
https://ncbi.nlm.nih.gov/pubmed/30978213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215232
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker